Shares of CRISPR Therapeutics plunged dramatically Wednesday after the U.S. Food and Drug Administration (FDA) placed a clinical hold on a planned sickle cell disease treatment the company was in … Continue Reading FDA Chains Clinical Hold on CRISPR/ Vertex Sickle Cell Disease IND
HIV-infected patients experience a dysfunction in a certain type of immune cell: the follicular helper T (Tfh) cell. A team of Japanese scientists have used CRISPR-cas9 to destroy the … Continue Reading CRISPR Offers Hope of “Functional Cures” for HIV
Scientists have successfully developed a far easier way to manipulate different genes by using a common research model, baker’s yeast. CRISPR has before helped refine and accelerate the … Continue Reading CRISPR Used for High-Throughput Genetic Assessment
Caspex Marks a New Series of Opportunities for Genomics Fusion of CRISPR and APEX2 Stands to Bolster Genome Mapping Capabilities
The Cas9 used for this experiment was catalytically inactive, known as dCas9, and lacked endonuclease potential. [Bill Oxford/Getty Images] Researchers from the Broad Institute invented a new … Continue Reading Caspex Marks a New Series of Opportunities for Genomics Fusion of CRISPR and APEX2 Stands to Bolster Genome Mapping Capabilities
A study at Karolinska Institutet in Sweden has revealed that CRISPR-Cas9 gene editing could favor mutations in the most common cancer-causing gene. What does it mean for the first CRISPR … Continue Reading Scientists Warn CRISPR Therapy Could Cause Cancer as First Human Trials Take Place
Two papers published today in Nature Medicine are raising a new potential red flag with CRISPR-Cas9 gene editing: Human cells that are successfully edited in the lab may have a … Continue Reading CRISPR Risks? Researchers Stoke Fears of Cancer in Gene-Edited Cells
CRISPR Therapeutics is using its proprietary CRISPR-Cas9 gene editing platform to develop transformative medicines. In this image, the Cas9 nuclease (whitish form) is being directed by a single-guide RNA (yellowish … Continue Reading Supplement: CRISPR Enters the Clinic Using CRISPR-Altered Cells to Fight Disease
Editing cells’ genomes with CRISPR-Cas9 might increase the risk that the altered cells, intended to treat disease, will trigger cancer, two studies published on Monday warn — a potential game-changer for … Continue Reading A serious new hurdle for CRISPR: Edited cells might cause cancer, find two studies
When the Japanese researcher Shinya Yamanaka managed to reprogram adult cells into an embryonic-like state to yield induced pluripotent stem cells (iPSCs), this was supposed to herald a revolution in … Continue Reading Regenerating the Body With Stem Cells – Hype or Hope?
The emergence of CRISPR/Cas9 technologies has enabled almost unlimited gene editing opportunities. Not only could it be used as a therapeutic tool, the genome editing tool could kickstart a revolution … Continue Reading CRISPR/Cas9: Could the Gene Editing Technology be the Future of Drug Discovery?
CRISPR-Cas9 has taken the world by storm in just a few years with the promise of making genome editing much easier and faster than ever before. But how does this … Continue Reading A Review of CRISPR-Cas9: How is the Gene Editing Tool Changing the World?
HIV research has come a long way since the disease was discovered in the 1980’s. Antiretroviral therapy was a major milestone that has changed the lives of millions, but the … Continue Reading An HIV Cure by 2020? A Review of the Future of HIV Therapy